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PMC ID
PMID
Rodriguez, Larry; Diedrich, Jolene; Sun, Le; Tsu, Blake; Kairs, Stefanie; Vlkolinsky, Roman; Barnes, Christopher A; Martins, Aline M A; Roberto, Marisa; Yates 3rd, John R
Patch-Clamp Single-Cell Proteomics in Acute Brain Slices: A Framework for Recording, Retrieval, and Interpretation.
ACS Chemical Neuroscience
17
1303-1315
2026 Apr 1
41854050
Holguin, Gabriel; Martin-Fardon, Rémi
Modulatory effects of orexin and dynorphin on stress-related alcohol seeking and relapse: pivotal role of the posterior paraventricular nucleus of the thalamus.
Frontiers in Pharacology
17
1729040
2026 Jan
PMC12883789
41669681
Borgonetti, Vittoria; St Onge, Celsey M; Cruz, Bryan; Zalfa, Cristina; Nadav, Tali; Roberts, Amanda J; Galeotti, Nicoletta; Bajo, Michal; Roberto, Marisa
Targeting IL-6 as a novel therapeutic approach for alcohol abstinence - related mechanical allodynia.
Neuropharmacology
278
110584
2025 Nov 1
PMC12341569
40588184
Quezada, Ava; Lord, Kevin; Alcantara, Cheldon; Delahunty, Claire; Kim, Kevin; Okamoto, Olivia; Yates 3rd, John R; Okumura, Cheryl Ym
Lysosomal permeabilization by Group A Streptococcus releases proteins into the macrophage cytosol
bioRxiv : the preprint server for biology
2025 Oct 25
Guo, Yinliang; Li, Yiheng; Chen, Sihan; Wu, Yige; Poll, Oscar; Ren, Zhouyang; Liu, Zhonglin; Vlkolinsky, Roman; Bajo, Michal; Prier, Christopher K; Xiao, Kai-Jiong; Cravatt, Benjamin F; Roberto, Marisa; Baran, Phil S
Scalable total synthesis of saxitoxin and related natural products.
Nature
646
351-357
2025 Oct
Hashimoto, Joel G; Mangieri, Regina A; Roberts, Amanda J; Lime, Turner; Davis, Brett A; Carbone, Lucia; Roberto, Marisa; Guizzetti, Marina
Alcohol dependence-induced astrocyte immune activation in the nucleus accumbens.
Neurobiology of disease
217
2025 Nov 3
PMC12721001
41192645
Varodayan, Florence P; Erikson, Chloe M; Scroger, Marcis V; Roberto, Marisa
Noradrenergic Mechanisms and Circuitry of Hyperkatifeia in Alcohol Use Disorder.
Biological Psychiatry
97
580-589
2025 Mar 15
Turner, Natalie P; Bajo, Michal; Roberts, Amanda J; Roberto, Marisa; Yates 3rd, John R
The effects of Alcohol Dependence on the CSF Proteome in Mice: Evidence for Blood-Brain Barrier Dysfunction and Neuroinflammation.
Neurobiol Dis
219
107254
2026 Feb
PMC12906712
41478511
Moss, Emaya M; Batsaikhan, Enkhzul; Cruz, Bryan; Steinman, Michael Q; Roberto, Marisa; Kirson, Dean
Oxytocin significantly enhances GABAergic transmission in the central amygdala of alcohol-naïve and alcohol-dependent female rats.
Neuropharmacology
279
2025 Nov 15
PMC12558444
40784544
Zhang, Xu; Vlkolinsky, Roman; Wu, Chongyang; Dolatabadi, Nima; Scott, Henry; Prikhodko, Olga; Zhang, Andrew; Blanco, Mayra; Lang, Nhi; Piña-Crespo, Juan; Nakamura, Tomohiro; Roberto, Marisa; Lipton, Stuart A
S-Nitrosylation of CRTC1 in Alzheimer's disease impairs CREB-dependent gene expression induced by neuronal activity.
Proc Natl Acad Sci U S A
122
e2418179122
2025 Mar 04
11892585
40014571
Guizzetti, Marina; Mangieri, Regina A; Ezerskiy, Lubov A; Hashimoto, Joel G; Bajo, Michal; Farris, Sean P; Homanics, Gregg E; Lasek, Amy W; Mayfield, R Dayne; Messing, Robert O; Roberto, Marisa
Astrocytes and Alcohol Throughout the Lifespan.
Biological Psychiatry
99
9-20
2026 Jan 1
12229257
40311830
Favoretto, Cristiane Aparecida; Nguyen, Allyson; Chacon, Gabriela R; Roberts, Amanda J; Nadav, Tali; Ranjan, Saumya; Bertotto, Luisa Becker; Cruz, Fábio Cardoso; Zorrilla, Eric P
Impacts of chronic intermittent ethanol vapor and predator odor on ethanol intake and striatal D1 and CB1 cannabinoid receptor-expressing medium spiny neurons.
Front Neurosci
19
1568952
2025
12149174
40497136
Dunning, Jeffery L; Lopez, Catherine; Krull, Colton; Kreifeldt, Max; Angelo, Maggie; Shu, Leeann; Ramakrishnan, Charu; Deisseroth, Karl; Contet, Candice
The parasubthalamic nucleus refeeding ensemble delays feeding initiation and hastens water drinking.
Mol Psychiatry
30
37-49
2025 Jan
11649566
38965421
Borgonetti, Vittoria; St Onge, Celsey M; Cruz, Bryan; Zalfa, Cristina; Nadav, Tali; Roberts, Amanda J; Galeotti, Nicoletta; Bajo, Michal; Roberto, Marisa
Targeting IL-6 as a novel therapeutic approach for alcohol abstinence - related mechanical allodynia.
Neuropharmacology
278
110584
2025 Nov 01
12341569
40588184
Lovinger, David M; Roberto, Marisa
Synaptic Effects Induced by Alcohol.
Curr Top Behav Neurosci
71
217-308
2025
11104446
36765015
Escudero, Berta; Kreifeldt, Max; Fleck, Kiera; Lopez, Catherine; Contet, Candice; Orio, Laura
Plasma apolipoproteins and memory function in alcohol use disorder: Findings in male C57BL/6J mice and men suggest a role for APOAI.
Alcohol Clin Exp Res (Hoboken)
49
2278-2293
2025 Aug 22
40846662
Vozella, Valentina; Borgonetti, Vittoria; Cruz, Bryan; Onge, Celsey M St; Bullard, Ryan; Vlkolinsky, Roman; Ceballos, Diego Gomez; Ozburn, Angela R; Roberts, Amanda J; Ciccocioppo, Roberto; Bajo, Michal; Roberto, Marisa
Apremilast reduces co-occurring alcohol drinking and mechanical allodynia and regulates central amygdala GABAergic transmission.
JCI Insight
10
2025 Apr 22
12016922
40260918
Anjos-Santos, Alexia; Erikson, Chloe Michelle; Flores-Ramirez, Francisco J; Rodriguez, Larry; Barchiesi, Riccardo; Vozella, Valentina; Borgonetti, Vittoria; Cruz, Bryan; Zalfa, Cristina; Hughes, Kiley; Gandhi, Pauravi; Bajo, Michal; Vlkolinsky, Roman; Mayfield, R Dayne; Martin-Fardon, Rémi; Roberto, Marisa
Noradrenaline Modulates Central Amygdala GABA Transmission and Alcohol Drinking in Female Rats.
Biological Psychiatry
99
21-23
2026 Jan 1
12369889
40194754
Varodayan, Florence P; Erikson, Chloe M; Scroger, Marcis V; Roberto, Marisa
Noradrenergic Mechanisms and Circuitry of Hyperkatifeia in Alcohol Use Disorder.
Biol Psychiatry
97
580-589
2025 Mar 15
11839382
39304172
Kreifeldt, Max; Okhuarobo, Agbonlahor; Dunning, Jeffery L; Lopez, Catherine; Macedo, Giovana; Sidhu, Harpreet; Contet, Candice
Mouse parasubthalamic Crh neurons drive alcohol drinking escalation and behavioral disinhibition.
bioRxiv
2024 Jul 10
11257461
39026704
Cruz, Bryan; Vozella, Valentina; Borgonetti, Vittoria; Bullard, Ryan; Bianchi, Paula C; Kirson, Dean; Bertotto, Luisa B; Bajo, Michal; Vlkolinsky, Roman; Messing, Robert O; Zorrilla, Eric P; Roberto, Marisa
Chemogenetic inhibition of central amygdala CRF-expressing neurons decreases alcohol intake but not trauma-related behaviors in a rat model of post-traumatic stress and alcohol use disorder.
Mol Psychiatry
29
2611-2621
2024 Sep
11415545
38509197
Flores-Ramirez, Francisco J; Illenberger, Jessica M; Pascasio, Glenn; Terenius, Lars; Martin-Fardon, Rémi
LY2444296, a κ-opioid receptor antagonist, selectively reduces alcohol drinking in male and female Wistar rats with a history of alcohol dependence.
Sci Rep
14
5804
2024 Mar 09
10925033
38461355
Illenberger, Jessica M; Flores-Ramirez, Francisco J; Pascasio, Glenn; Franco, Marissa; Mendonsa, Brandon; Martin-Fardon, Rémi
Pivotal role of orexin signaling in the posterior paraventricular nucleus of the thalamus during the stress-induced reinstatement of oxycodone-seeking behavior.
J Psychopharmacol
38
647-660
2024 Jul
11407285
38888086
McClatchy, Daniel B; Yates 3rd, John R
Acid cleavable biotin-alkyne improves sensitivity for direct detection of biotin labeled peptides in BONCAT analysis.
bioRxiv
2024 Jul 17
11275937
39071280
Bertotto, Luísa B; Lampson-Stixrud, Dolly; Sinha, Anushka; Rohani, Nicki K; Myer, Isabella; Zorrilla, Eric P
Effects of the Phosphodiesterase 10A Inhibitor MR1916 on Alcohol Self-Administration and Striatal Gene Expression in Post-Chronic Intermittent Ethanol-Exposed Rats.
Cells
13
2024 Feb 09
10886814
38391934
McClatchy, Daniel B; Garrett, Patrick T; Jung, Titus; Diedrich, Jolene K; Yates 3rd, John R
Acid Cleavable Biotin-Alkyne Improves Sensitivity for Direct Detection of Biotin Labeled Peptides in Biorthogonal Noncanonical Amino Acid Tagging Analysis.
J Proteome Res
23
5487-5497
2024 Dec 06
12067412
39579148
Oasa, Sho; Sezgin, Erdinc; Ma, Yuelong; Horne, David A; Radmilović, Mihajlo D; Jovanović-Talisman, Tijana; Martin-Fardon, Rémi; Vukojević, Vladana; Terenius, Lars
Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane.
Transl Psychiatry
14
477
2024 Nov 24
11586411
39582064
Patel, Reesha R; Gandhi, Pauravi; Spencer, Kathryn; Salem, Nihal A; Erikson, Chloe M; Borgonetti, Vittoria; Vlkolinsky, Roman; Rodriguez, Larry; Nadav, Tali; Bajo, Michal; Roberts, Amanda J; Dayne Mayfield, R; Roberto, Marisa
Functional and morphological adaptation of medial prefrontal corticotropin releasing factor receptor 1-expressing neurons in male mice following chronic ethanol exposure.
Neurobiol Stress
31
100657
2024 Jul
11231756
38983690
Vlkolinsky, Roman; Khom, Sophia; Vozella, Valentina; Bajo, Michal; Roberto, Marisa
Withdrawal from chronic alcohol impairs the serotonin-mediated modulation of GABAergic transmission in the infralimbic cortex in male rats.
Neurobiol Dis
199
106590
2024 Sep
11412312
38996987
Carrette, L L G; Santos, A; Brennan, M; Othman, D; Collazo, A; George, O
Antagonists of the stress and opioid systems restore the functional connectivity of the prefrontal cortex during alcohol withdrawal through divergent mechanisms.
bioRxiv
2024 Jan 14
10592857
37873478
Mason, Barbara J; Estey, David; Roberts, Amanda; de Guglielmo, Giordano; George, Olivier; Light, John; Stoolmiller, Mike; Quello, Susan; Skinner, Michael; Shadan, Farhad; Begovic, Adnan; Kyle, Mark C; Harris, R Adron
A reverse translational study of PPAR-α agonist efficacy in human and rodent models relevant to alcohol use disorder.
Neurobiol Stress
29
100604
2024 Mar
10825428
38292518
Okhuarobo, Agbonlahor; Kreifeldt, Max; Gandhi, Pauravi J; Lopez, Catherine; Martinez, Briana; Fleck, Kiera; Bajo, Michal; Bhattacharyya, Pushpita; Dopico, Alex M; Roberto, Marisa; Roberts, Amanda J; Homanics, Gregg E; Contet, Candice
Ethanol's interaction with BK channel α subunit residue K361 does not mediate behavioral responses to alcohol in mice.
Mol Psychiatry
29
529-542
2024 Feb
11116116
38135755
Borgonetti, Vittoria; Vozella, Valentina; Ware, Tim; Cruz, Bryan; Bullard, Ryan; Cravatt, Benjamin F; Galeotti, Nicoletta; Roberto, Marisa
Excessive alcohol intake produces persistent mechanical allodynia and dysregulates the endocannabinoid system in the lumbar dorsal root ganglia of genetically-selected Marchigian Sardinian alcohol-preferring rats.
Pharmacol Res
209
107462
2024 Nov
11834946
39396766
Miliano, Cristina; Natividad, Luis A; Quello, Susan; Stoolmiller, Mike; Gregus, Ann M; Buczynski, Matthew W; Mason, Barbara J
The Predictive Value of Plasma Bioactive Lipids on Craving in Human Volunteers With Alcohol Use Disorder.
Biol Psychiatry Glob Open Sci
4
100368
2024 Nov
11400622
39282655
Athanason, A C; Nadav, T; Cates-Gatto, C; Roberts, A J; Roberto, M; Varodayan, F P
Chronic ethanol alters adrenergic receptor gene expression and produces cognitive deficits in male mice.
Neurobiol Stress
24
100542
2023 May
10184141
37197395
de Guglielmo, Giordano; Simpson, Sierra; Kimbrough, Adam; Conlisk, Dana; Baker, Robert; Cantor, Maxwell; Kallupi, Marsida; George, Olivier
Voluntary and forced exposure to ethanol vapor produces similar escalation of alcohol drinking but differential recruitment of brain regions related to stress, habit, and reward in male rats.
Neuropharmacology
222
109309
2023 Jan 01
10022477
36334765
Grigsby, Kolter B; Mangieri, Regina A; Roberts, Amanda J; Lopez, Marcelo F; Firsick, Evan J; Townsley, Kayla G; Beneze, Alan; Bess, Jessica; Eisenstein, Toby K; Meissler, Joseph J; Light, John M; Miller, Jenny; Quello, Susan; Shadan, Farhad; Skinner, Michael; Aziz, Heather C; Metten, Pamela; Morrisett, Richard A; Crabbe, John C; Roberto, Marisa; Becker, Howard C; Mason, Barbara J; Ozburn, Angela R
Preclinical and clinical evidence for suppression of alcohol intake by apremilast.
J Clin Invest
133
2023 Mar 15
10014105
36656645
Cruz, Bryan; Vozella, Valentina; Carper, Benjamin A; Xu, Joy C; Kirson, Dean; Hirsch, Shawn; Nolen, Tracy; Bradley, Lauren; Fain, Katie; Crawford, Meg; Kosten, Thomas R; Zorrilla, Eric P; Roberto, Marisa
FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder.
Neuropsychopharmacology
48
1144-1154
2023 Jul
10267127
36396784
Flores-Ramirez, Francisco J; Varodayan, Florence P; Patel, Reesha R; Illenberger, Jessica M; Di Ottavio, Francesca; Roberto, Marisa; Martin-Fardon, Rémi
Blockade of orexin receptors in the infralimbic cortex prevents stress-induced reinstatement of alcohol-seeking behaviour in alcohol-dependent rats.
Br J Pharmacol
180
1500-1515
2023 Jun
10577928
36537731
Doyle, Michelle R; Martinez, Angelica R; Qiao, Ran; Dirik, Selen; Di Ottavio, Francesca; Pascasio, Glenn; Martin-Fardon, Rémi; Benner, Christopher; George, Olivier; Telese, Francesca; de Guglielmo, Giordano
Strain and sex-related behavioral variability of oxycodone dependence in rats.
Neuropharmacology
237
109635
2023 Oct 01
10353778
37327971
Macedo, Giovana C; Kreifeldt, Max; Goulding, Scott P; Okhuarobo, Agbonlahor; Sidhu, Harpreet; Contet, Candice
Chronic MAP4343 reverses escalated alcohol drinking in a mouse model of alcohol use disorder.
Neuropsychopharmacology
48
821-830
2023 Apr
10066354
36670228
Okhuarobo, Agbonlahor; Angelo, Maggie; Bolton, Jessica L; Lopez, Catherine; Igbe, Ighodaro; Baram, Tallie Z; Contet, Candice
Influence of early-life adversity on responses to acute and chronic ethanol in female mice.
Alcohol Clin Exp Res (Hoboken)
47
336-347
2023 Feb
9992294
36462937
Carrette, Lieselot L G; Kimbrough, Adam; Davoudian, Pasha A; Kwan, Alex C; Collazo, Andres; George, Olivier
Hyperconnectivity of Two Separate Long-Range Cholinergic Systems Contributes to the Reorganization of the Brain Functional Connectivity during Nicotine Withdrawal in Male Mice.
eNeuro
10
2023 Jun
10306126
37295945
Sanna, Pietro Paolo; Cabrelle, Chiara; Kawamura, Tomoya; Mercatelli, Daniele; O'Connor, Nathan; Roberts, Amanda J; Repunte-Canonigo, Vez; Giorgi, Federico M
A History of Repeated Alcohol Intoxication Promotes Cognitive Impairment and Gene Expression Signatures of Disease Progression in the 3xTg Mouse Model of Alzheimer's Disease.
eNeuro
10
2023 Jul
10337838
37308288
Terenius, Lars; Oasa, Sho; Sezgin, Erdinc; Ma, Yuelong; Horne, David; Radmiković, Mihajlo; Jovanović-Talisman, Tijana; Martin-Fardon, Remi; Vukojevic, Vladana
Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane.
Res Sq
2023 Jul 21
10371157
37503185
Vozella, Valentina; Cruz, Bryan; Feldman, Hannah C; Bullard, Ryan; Bianchi, Paula C; Natividad, Luis A; Cravatt, Benjamin F; Zorrilla, Eric P; Ciccocioppo, Roberto; Roberto, Marisa
Sexually dimorphic effects of monoacylglycerol lipase inhibitor MJN110 on stress-related behaviour and drinking in Marchigian Sardinian alcohol-preferring rats.
Br J Pharmacol
180
3130-3145
2023 Dec
10805956
37488777
McGregor, Ronald; Matzeu, Alessandra; Thannickal, Thomas C; Wu, Frank; Cornford, Marcia; Martin-Fardon, Rémi; Siegel, Jerome M
Sensitivity of Hypocretin System to Chronic Alcohol Exposure: A Human and Animal Study.
Neuroscience
522
10-Jan
2023 Jul 01
10681027
37121379
Varodayan, F P; Pahng, A R; Davis, T D; Gandhi, P; Bajo, M; Steinman, M Q; Kiosses, W B; Blednov, Y A; Burkart, M D; Edwards, S; Roberts, A J; Roberto, M
Chronic ethanol induces a pro-inflammatory switch in interleukin-1β regulation of GABAergic signaling in the medial prefrontal cortex of male mice.
Brain Behav Immun
110
125-139
2023 May
10106421
36863493
Siddiqi, Mahum T; Podder, Dhruba; Pahng, Amanda R; Athanason, Alexandria C; Nadav, Tali; Cates-Gatto, Chelsea; Kreifeldt, Max; Contet, Candice; Roberts, Amanda J; Edwards, Scott; Roberto, Marisa; Varodayan, Florence P
Prefrontal cortex glutamatergic adaptations in a mouse model of alcohol use disorder.
Addict Neurosci
9
2023 Dec 15
10752437
38152067
Khom, Sophia; Borgonetti, Vittoria; Vozella, Valentina; Kirson, Dean; Rodriguez, Larry; Gandhi, Pauravi; Bianchi, Paula Cristina; Snyder, Angela; Vlkolinsky, Roman; Bajo, Michal; Oleata, Christopher S; Ciccocioppo, Roberto; Roberto, Marisa
Glucocorticoid receptors regulate central amygdala GABAergic synapses in Marchigian-Sardinian alcohol-preferring rats.
Neurobiol Stress
25
100547
2023 Jul
10401345
37547774
Borgonetti, Vittoria; Cruz, Bryan; Vozella, Valentina; Khom, Sophia; Steinman, Michael Q; Bullard, Ryan; D'Ambrosio, Shannon; Oleata, Christopher S; Vlkolinsky, Roman; Bajo, Michal; Zorrilla, Eric P; Kirson, Dean; Roberto, Marisa
IL-18 Signaling in the Rat Central Amygdala Is Disrupted in a Comorbid Model of Post-Traumatic Stress and Alcohol Use Disorder.
Cells
12
2023 Jul 27
10416956
37566022
Illenberger, Jessica M; Flores-Ramirez, Francisco J; Matzeu, Alessandra; Lütjens, Robert; Martin-Fardon, Rémi
ADX106772, an mGlu2 receptor positive allosteric modulator, selectively attenuates oxycodone taking and seeking.
Neuropharmacology
238
109666
2023 Nov 01
10529136
37463637
Illenberger, Jessica M; Flores-Ramirez, Francisco J; Pascasio, Glenn; Matzeu, Alessandra; Martin-Fardon, Rémi
Daily treatment with the dual orexin receptor antagonist DORA-12 during oxycodone abstinence decreases oxycodone conditioned reinstatement.
Neuropharmacology
239
109685
2023 Nov 15
10529002
37579870
Cruz, Bryan; Borgonetti, Vittoria; Bajo, Michal; Roberto, Marisa
Sex-dependent factors of alcohol and neuroimmune mechanisms.
Neurobiol Stress
26
100562
2023 Sep
10432974
37601537
Borgonetti, Vittoria; Roberts, Amanda J; Bajo, Michal; Galeotti, Nicoletta; Roberto, Marisa
Chronic alcohol induced mechanical allodynia by promoting neuroinflammation: A mouse model of alcohol-evoked neuropathic pain.
Br J Pharmacol
180
2377-2392
2023 Sep
10898491
37050867
Illenberger, Jessica M; Flores-Ramirez, Francisco J; Matzeu, Alessandra; Mason, Barbara J; Martin-Fardon, Rémi
Suvorexant, an FDA-approved dual orexin receptor antagonist, reduces oxycodone self-administration and conditioned reinstatement in male and female rats.
Front Pharmacol
14
1127735
2023
10172671
37180716
Rodriguez, Larry; Kirson, Dean; Wolfe, Sarah A; Patel, Reesha R; Varodayan, Florence P; Snyder, Angela E; Gandhi, Pauravi J; Khom, Sophia; Vlkolinsky, Roman; Bajo, Michal; Roberto, Marisa
Alcohol Dependence Induces CRF Sensitivity in Female Central Amygdala GABA Synapses.
Int J Mol Sci
23
2022 Jul 16
9318832
35887190
Shah, Tanvi; Dunning, Jeffery L; Contet, Candice
At the heart of the interoception network: Influence of the parasubthalamic nucleus on autonomic functions and motivated behaviors.
Neuropharmacology
204
108906
2022 Feb 15
8688299
34856204
Aldridge, Gabriel M; Zarin, Tyler A; Brandner, Adam J; George, Olivier; Gilpin, Nicholas W; Repunte-Canonigo, Vez; Sanna, Pietro P; Koob, George F; Vendruscolo, Leandro F; Schmeichel, Brooke E
Effects of single and dual hypocretin-receptor blockade or knockdown of hypocretin projections to the central amygdala on alcohol drinking in dependent male rats.
Addict Neurosci
3
2022 Sep
9365098
35965958
Bowen, Michael T; George, Olivier; Muskiewicz, Dawn E; Hall, F Scott
FACTORS CONTRIBUTING TO THE ESCALATION OF ALCOHOL CONSUMPTION.
Neurosci Biobehav Rev
132
730-756
2022 Jan
8892842
34839930
Flores-Ramirez, Francisco J; Illenberger, Jessica M; Pascasio, Glenn E; Matzeu, Alessandra; Mason, Barbara J; Martin-Fardon, Rémi
Alternative use of suvorexant (Belsomra®) for the prevention of alcohol drinking and seeking in rats with a history of alcohol dependence.
Front Behav Neurosci
16
1085882
2022
9813433
36620860
Patel, Reesha R; Varodayan, Florence P; Herman, Melissa A; Jimenez, Vanessa; Agnore, Rebecca; Gao, Lina; Bajo, Michal; Cuzon Carlson, Verginia C; Walter, Nicole A; Fei, Suzanne S; Grant, Kathleen A; Roberto, Marisa
Synaptic effects of IL-1β and CRF in the central amygdala after protracted alcohol abstinence in male rhesus macaques.
Neuropsychopharmacology
47
847-856
2022 Mar
8882167
34837077
Laque, Amanda; Wagner, Grant E; Matzeu, Alessandra; De Ness, Genna L; Kerr, Tony M; Carroll, Ayla M; de Guglielmo, Giordano; Nedelescu, Hermina; Buczynski, Matthew W; Gregus, Ann M; Jhou, Thomas C; Zorrilla, Eric P; Martin-Fardon, Remi; Koya, Eisuke; Ritter, Robert C; Weiss, Friedbert; Suto, Nobuyoshi
Linking drug and food addiction via compulsive appetite.
Br J Pharmacol
179
2589-2609
2022 Jun
9081129
35023154
Gutierrez, Arnold; Creehan, Kevin M; de Guglielmo, Giordano; Roberts, Amanda J; Taffe, Michael A
Behavioral effects of ethanol in the Red Swamp Crayfish (Procambarus clarkii).
J Exp Anal Behav
117
472-492
2022 May
11528345
35261037
Varodayan, Florence P; Patel, Reesha R; Matzeu, Alessandra; Wolfe, Sarah A; Curley, Dallece E; Khom, Sophia; Gandhi, Pauravi J; Rodriguez, Larry; Bajo, Michal; D'Ambrosio, Shannon; Sun, Hui; Kerr, Tony M; Gonzales, Rueben A; Leggio, Lorenzo; Natividad, Luis A; Haass-Koffler, Carolina L; Martin-Fardon, Rémi; Roberto, Marisa
The Amygdala Noradrenergic System Is Compromised With Alcohol Use Disorder.
Biol Psychiatry
91
1008-1018
2022 Jun 15
9167785
35430085
Kreifeldt, Max; Herman, Melissa A; Sidhu, Harpreet; Okhuarobo, Agbonlahor; Macedo, Giovana C; Shahryari, Roxana; Gandhi, Pauravi J; Roberto, Marisa; Contet, Candice
Central amygdala corticotropin-releasing factor neurons promote hyponeophagia but do not control alcohol drinking in mice.
Mol Psychiatry
27
2502-2513
2022 May
9149056
35264727
Kirson, Dean; Spierling Bagsic, Samantha R; Murphy, Jiayuan; Chang, Hang; Vlkolinsky, Roman; Pucci, Sarah N; Prinzi, Julia; Williams, Casey A; Fang, Savannah Y; Roberto, Marisa; Zorrilla, Eric P
Decreased excitability of leptin-sensitive anterior insula pyramidal neurons in a rat model of compulsive food demand.
Neuropharmacology
208
108980
2022 May 01
9055870
35122838
Simpson, Sierra; Mclellan, Rio; Wellmeyer, Emma; Matalon, Frederic; George, Olivier
Drugs and Bugs: The Gut-Brain Axis and Substance Use Disorders.
J Neuroimmune Pharmacol
17
33-61
2022 Jun
9074906
34694571
Khom, Sophia; Rodriguez, Larry; Gandhi, Pauravi; Kirson, Dean; Bajo, Michal; Oleata, Christopher S; Vendruscolo, Leandro F; Mason, Barbara J; Roberto, Marisa
Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats.
Neurobiol Dis
164
105610
2022 Mar
9301881
34995754
Flores-Ramirez, Francisco J; Matzeu, Alessandra; Sánchez-Marín, Laura; Martin-Fardon, Rémi
Blockade of corticotropin-releasing factor-1 receptors in the infralimbic cortex prevents stress-induced reinstatement of alcohol seeking in male Wistar rats: Evidence of interaction between CRF1 and orexin receptor signaling.
Neuropharmacology
210
109046
2022 Jun 01
9176217
35341789
Wolfe, Sarah A; Vozella, Valentina; Roberto, Marisa
The Synaptic Interactions of Alcohol and the Endogenous Cannabinoid System.
Alcohol Res
42
3
2022
8843413
35223337
Patel, Reesha R; Wolfe, Sarah A; Borgonetti, Vittoria; Gandhi, Pauravi J; Rodriguez, Larry; Snyder, Angela E; D'Ambrosio, Shannon; Bajo, Michal; Domissy, Alain; Head, Steven; Contet, Candice; Dayne Mayfield, R; Roberts, Amanda J; Roberto, Marisa
Ethanol withdrawal-induced adaptations in prefrontal corticotropin releasing factor receptor 1-expressing neurons regulate anxiety and conditioned rewarding effects of ethanol.
Mol Psychiatry
27
3441-3451
2022 Aug
9708587
35668157
Sakoulas, Eleanna M; Bertotto, Luisa B; Logrip, Marian L; Lin, Katrina; Pimentel, Anastasia E; Cruz, Bryan; Vozella, Valentina; Roberto, Marisa; Zorrilla, Eric P
Benztropine Reduces Reacquisition of Alcohol Self-Administration in Rats with Stress History: Role of FKBP5.
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Kirson, Dean; Steinman, Michael Q; Wolfe, Sarah A; Spierling Bagsic, Samantha R; Bajo, Michal; Sureshchandra, Suhas; Oleata, Christopher S; Messaoudi, Ilhem; Zorrilla, Eric P; Roberto, Marisa
Sex and context differences in the effects of trauma on comorbid alcohol use and post-traumatic stress phenotypes in actively drinking rats.
J Neurosci Res
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Glucocorticoid receptor modulators decrease alcohol self-administration in male rats.
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Simpson, Sierra; Chen, Yueyi; Wellmeyer, Emma; Smith, Lauren C; Aragon Montes, Brianna; George, Olivier; Kimbrough, Adam
The Hidden Brain: Uncovering Previously Overlooked Brain Regions by Employing Novel Preclinical Unbiased Network Approaches.
Front Syst Neurosci
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Smith, Lauren C; Tieu, Lani; Suhandynata, Raymond T; Boomhower, Brent; Hoffman, Melissa; Sepulveda, Yadira; Carrette, Lieselot L G; Momper, Jeremiah D; Fitzgerald, Robert L; Hanham, Kate; Dowling, Joseph; Kallupi, Marsida; George, Olivier
Cannabidiol reduces withdrawal symptoms in nicotine-dependent rats.
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Glucocorticoid Receptor Antagonist Mifepristone Does Not Alter Innate Anxiety-Like Behavior in Genetically-Selected Marchigian Sardinian (msP) Rats.
Int J Mol Sci
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Patel, Reesha R; Wolfe, Sarah A; Bajo, Michal; Abeynaike, Shawn; Pahng, Amanda; Borgonetti, Vittoria; D'Ambrosio, Shannon; Nikzad, Rana; Edwards, Scott; Paust, Silke; Roberts, Amanda J; Roberto, Marisa
IL-10 normalizes aberrant amygdala GABA transmission and reverses anxiety-like behavior and dependence-induced escalation of alcohol intake.
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Mason, Barbara J
Medications to Treat Alcohol Use Disorder: Targeting the Dark Side.
Am J Psychiatry
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2021 05 01
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Steinman, Michael Q; Kirson, Dean; Wolfe, Sarah A; Khom, Sophia; D'Ambrosio, Shannon R; Spierling Bagsic, Samantha R; Bajo, Michal; Vlkolinský, Roman; Hoang, Noah K; Singhal, Anshita; Sureshchandra, Suhas; Oleata, Christopher S; Messaoudi, Ilhem; Zorrilla, Eric P; Roberto, Marisa
Importance of sex and trauma context on circulating cytokines and amygdalar GABAergic signaling in a comorbid model of posttraumatic stress and alcohol use disorders.
Mol Psychiatry
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Roberto, Marisa; Kirson, Dean; Khom, Sophia
The Role of the Central Amygdala in Alcohol Dependence.
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Kirson, Dean; Khom, Sophia; Rodriguez, Larry; Wolfe, Sarah A; Varodayan, Florence P; Gandhi, Pauravi J; Patel, Reesha R; Vlkolinsky, Roman; Bajo, Michal; Roberto, Marisa
Sex Differences in Acute Alcohol Sensitivity of Naïve and Alcohol Dependent Central Amygdala GABA Synapses.
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Benvenuti, Federica; Cannella, Nazzareno; Stopponi, Serena; Soverchia, Laura; Ubaldi, Massimo; Lunerti, Veronica; Vozella, Valentina; Cruz, Bryan; Roberto, Marisa; Ciccocioppo, Roberto
Effect of Glucocorticoid Receptor Antagonism on Alcohol Self-Administration in Genetically-Selected Marchigian Sardinian Alcohol-Preferring and Non-Preferring Wistar Rats.
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Mason, Barbara J; Heyser, Charles J
Alcohol Use Disorder: The Role of Medication in Recovery.
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Avchalumov, Yosef; Kreisler, Alison D; Xing, Nancy; Shayan, Amin A; Bharadwaj, Tejash; Watson, Jacob R; Sibley, Britta; Somkuwar, Sucharita S; Trenet, Wulfran; Olia, Sumaiya; Piña-Crespo, Juan C; Roberto, Marisa; Mandyam, Chitra D
Sexually dimorphic prelimbic cortex mechanisms play a role in alcohol dependence: protection by endostatin.
Neuropsychopharmacology
46
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2021 Oct
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Natividad, Luis A; Steinman, Michael Q; McGinn, M Adrienne; Sureshchandra, Suhas; Kerr, Tony M; Ciccocioppo, Roberto; Messaoudi, Ilhem; Edwards, Scott; Roberto, Marisa
Impaired hypothalamic feedback dysregulates brain glucocorticoid signaling in genetically-selected Marchigian Sardinian alcohol-preferring rats.
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Converging vulnerability factors for compulsive food and drug use.
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Kimbrough, Adam; Kallupi, Marsida; Smith, Lauren C; Simpson, Sierra; Collazo, Andres; George, Olivier
Characterization of the Brain Functional Architecture of Psychostimulant Withdrawal Using Single-Cell Whole-Brain Imaging.
eNeuro
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Kisby, Brent R; Farris, Sean P; McManus, Michelle M; Varodayan, Florence P; Roberto, Marisa; Harris, R Adron; Ponomarev, Igor
Alcohol Dependence in Rats Is Associated with Global Changes in Gene Expression in the Central Amygdala.
Brain Sci
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2021 Aug 29
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Matzeu, Alessandra; Martin-Fardon, Rémi
Blockade of corticotropin-releasing factor receptor 1 in the central amygdala prevents cocaine-seeking behaviour induced by orexin-A administered to the posterior paraventricular nucleus of the thalamus in male rats.
J Psychiatry Neurosci
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Matzeu, Alessandra; Martin-Fardon, Rémi
Cocaine-Seeking Behavior Induced by Orexin A Administration in the Posterior Paraventricular Nucleus of the Thalamus Is Not Long-Lasting: Neuroadaptation of the Orexin System During Cocaine Abstinence.
Front Behav Neurosci
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Staples, Miranda C; Herman, Melissa A; Lockner, Jonathan W; Avchalumov, Yosef; Kharidia, Khush M; Janda, Kim D; Roberto, Marisa; Mandyam, Chitra D
Isoxazole-9 reduces enhanced fear responses and retrieval in ethanol-dependent male rats.
J Neurosci Res
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Chronic ethanol exposure differentially alters neuronal function in the medial prefrontal cortex and dentate gyrus.
Neuropharmacology
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Pavón, Francisco Javier; Polis, Ilham Y; Stouffer, David G; Cravatt, Benjamin F; Roberto, Marisa; Martin-Fardon, Rémi; Rodríguez de Fonseca, Fernando; Parsons, Loren H; Serrano, Antonia
Selective inhibition of monoacylglycerol lipase is associated with passive coping behavior and attenuation of stress-induced dopamine release in the medial prefrontal cortex.
Neurobiol Stress
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Matzeu, Alessandra; Martin-Fardon, Rémi
Targeting the orexin system for prescription opioid use disorder: Orexin-1 receptor blockade prevents oxycodone taking and seeking in rats.
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Kimbrough, Adam; Lurie, Daniel J; Collazo, Andres; Kreifeldt, Max; Sidhu, Harpreet; Macedo, Giovana Camila; D'Esposito, Mark; Contet, Candice; George, Olivier
Brain-wide functional architecture remodeling by alcohol dependence and abstinence.
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Matzeu, Alessandra; Martin-Fardon, Rémi
Targeting the Orexin System for Prescription Opioid Use Disorder.
Brain Sci
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Smith, Lauren C; George, Olivier
Advances in smoking cessation pharmacotherapy: Non-nicotinic approaches in animal models.
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