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Research Cores

The TSRI-ARC comprises five Research Components and three Cores: the Administrative Core, Animal Models Core, and Information Dissemination Core. This infrastructure addresses four fundamental needs: innovative science, essential core services, the introduction of new investigators, and education. The Research Components drive high-quality innovative science with a focus on neuroadaptive changes linked to relapse vulnerability from acute alcohol withdrawal to prolonged abstinence. The Administrative Core manages progress, resource allocation, and collaboration, while the Animal Models Core supports dependence induction, blood alcohol monitoring, and validation of animal models for human studies. The Center also fosters new investigators through resource sharing, seminars, and collaborations. Finally, the Dissemination Core connects with the San Diego community, translating research findings for medical professionals and the public.

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Administrative Core

The Administrative Core strives to provide leadership, facilitate resource sharing and collaborations, attract new investigators, and disseminate TSRI-ARC research findings.

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Dissemination Core

The Dissemination Core aims to disseminate research findings made by TSRI-ARC labs to the public through educational and outreach efforts, that target NIAAA-identified “Special Populations.”

 

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Animal Models Core

The Animal Models/Biological Measures Core facilitates TSRI-ARC and Center-At-Large research by providing standard operating procedures, developing and refining animal models of AUD, and providing preclinical and standardized biochemical testing.

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