Our research investigates the neurobiological underpinnings of alcohol use disorder (AUD) relapse, focusing on the role of the infralimbic cortex and central amygdala in stress-related affective dysregulation and compulsive alcohol-seeking behaviors, through a series of targeted experimental aims.
Our research investigates the neurobiological underpinnings of alcohol use disorder (AUD) relapse, focusing on the role of the infralimbic cortex and central amygdala in stress-related affective dysregulation and compulsive alcohol-seeking behaviors, through a series of targeted experimental aims.
Our research investigates the neurobiological underpinnings of alcohol use disorder (AUD) relapse, focusing on the role of the infralimbic cortex and central amygdala in stress-related affective dysregulation and compulsive alcohol-seeking behaviors, through a series of targeted experimental aims.
2025 Research Society on Alcohol Meeting, New Orleans, LA
"Researchers pinpoint brain cells that delay first bite of food"
July 2024
A set of neurons identified by Scripps Research scientists influence the start of eating and drinking.
"Researchers identify brain region involved in oxycodone relapse."
July 2024
Study by Scripps Research scientists suggests future therapies for opioid and alcohol addiction.
"How Neural Inhibition Could Reduce Alcohol Use"
March 2024
A Scripps Research team shows that suppressing the activity of certain stress neurons may decrease alcohol use—but not anxiety—in comorbid cases of post-traumatic stress disorder and alcohol use disorder.
"How Blocking a Neural Receptor Responsible for Addiction Could Reduce Alcohol Use"
March 2024
A Scripps Research team found that a new therapeutic that targets the kappa opioid receptor in the brain may reduce alcohol dependence.
"Scripps Research scientists give new insight into a molecular target of alcohol"
January 2024
By investigating a molecule in the brain tied to cellular communication, scientists uncover important information about the proteins that do—and do not—influence alcohol drinking behavior.
"Insomnia drug helps prevent oxycodone relapse, Scripps Research study shows"
September 2023
New findings suggest that treating insomnia can stop opioid-seeking behavior, even after ending treatment.
"Blocking glutamate release reduces oxycodone intake and seeking behavior"
July 2023
In a preclinical study, Scripps Research scientists show that the drug ADX106772 (Addex Therapeutics) reduced oxycodone intake and relapse, without disrupting the brain’s natural reward system.
"Excessive alcohol consumption may accelerate Alzheimer’s disease progression"
June 2023
Scripps Research and University of Bologna scientists showed how excessive alcohol consumption in animals can hasten cognitive decline in those genetically predisposed to Alzheimer’s disease.