The winners of the 2019 Larry Parsons Travel Award received assistance toward the Research Society on Alcoholism meeting taking place June 23-27, 2019 in Minneapolis, MN.

Congratulations to:

Sophia Khom

Jung Kim

Giovana de Macedo

Sarah Wolfe

For more information about this travel award and to learn more about our dear friend and scientific partner, Larry Parsons, please visit https://www.scripps.edu/parsons/Research.html

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The Volterra Conference website has been updated and has new information about the 2020 meeting!

HIGHlighted publication

Insula to ventral striatal projections mediate compulsive eating produced by intermittent access to palatable food

Samantha Spierling, Giordano de Guglielmo, Dean Kirson, Alison Kreisler, Marisa Roberto, Olivier George, and Eric Zorrilla

  • The insular cortex subserves visceral-emotional functions and, based on its afferent and efferent connections, likely plays a role in the negative reinforcement so important in the compulsive intake of food and drugs characteristic of eating and substance use disorders.

 

  • Female rats were given intermittent access to a highly palatable diet and a subset of rats demonstrated elevated progressive ratio responding, increased punished responding and irritability following withdrawal of the diet, all suggestive of increased compulsive-like behavior.​

Screen Shot 2019-08-27 at 3.10.07 PM.png

The Volterra Conference website has been updated and has new information about the 2020 meeting!

HIGHlighted publication

Insula to ventral striatal projections mediate compulsive eating produced by intermittent access to palatable food

Samantha Spierling, Giordano de Guglielmo, Dean Kirson, Alison Kreisler, Marisa Roberto, Olivier George, and Eric Zorrilla

  • The insular cortex subserves visceral-emotional functions and, based on its afferent and efferent connections, likely plays a role in the negative reinforcement so important in the compulsive intake of food and drugs characteristic of eating and substance use disorders.

 

  • Female rats were given intermittent access to a highly palatable diet and a subset of rats demonstrated elevated progressive ratio responding, increased punished responding and irritability following withdrawal of the diet, all suggestive of increased compulsive-like behavior.​

Screen Shot 2019-08-27 at 3.10.07 PM.png

The Volterra Conference website has been updated and has new information about the 2020 meeting!

HIGHlighted publication

Insula to ventral striatal projections mediate compulsive eating produced by intermittent access to palatable food

Samantha Spierling, Giordano de Guglielmo, Dean Kirson, Alison Kreisler, Marisa Roberto, Olivier George, and Eric Zorrilla

  • The insular cortex subserves visceral-emotional functions and, based on its afferent and efferent connections, likely plays a role in the negative reinforcement so important in the compulsive intake of food and drugs characteristic of eating and substance use disorders.

 

  • Female rats were given intermittent access to a highly palatable diet and a subset of rats demonstrated elevated progressive ratio responding, increased punished responding and irritability following withdrawal of the diet, all suggestive of increased compulsive-like behavior.​

Screen Shot 2019-08-27 at 3.10.07 PM.png

The Volterra Conference website has been updated and has new information about the 2020 meeting!

HIGHlighted publication

Insula to ventral striatal projections mediate compulsive eating produced by intermittent access to palatable food

Samantha Spierling, Giordano de Guglielmo, Dean Kirson, Alison Kreisler, Marisa Roberto, Olivier George, and Eric Zorrilla

  • The insular cortex subserves visceral-emotional functions and, based on its afferent and efferent connections, likely plays a role in the negative reinforcement so important in the compulsive intake of food and drugs characteristic of eating and substance use disorders.

 

  • Female rats were given intermittent access to a highly palatable diet and a subset of rats demonstrated elevated progressive ratio responding, increased punished responding and irritability following withdrawal of the diet, all suggestive of increased compulsive-like behavior.​

  • This more compulsive-like sub-population showed decreased lever pressing upon optoinhibition of the anterior insular cortex to nucleus accumbens connection and also had a unique endocrine profile.

 

  • These results highlight the importance of the projections from the anterior insular cortex to the nucleus accumbens in compulsive-like behavior and support this model’s use to further study addictive disorders, such as alcohol use disorder.

This paper highlights the essential intercollaboratory efforts of our ARC team

Congratulations to

Dr. Samantha Spierling!!!

TSRI Graduate School PhD, 2019

Dr. Spierling is currently a biostatistician at Scripps Health.  She supports trainee- and investigator-initiated translational research as part of the Scripps Hub Academic Research Core (SHARC).

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